Abstract #5012

3D magnetic resonance fingerprinting in preoperative prediction of glioma grade and ki67 increment index

Linkun Wang¹, Yaping Wu², Wei Wei², Xinyao Liu³, Yan Bai², and Meiyun Wang²

¹Department of Radiology, the People’s Hospital of Henan University, Zhengzhou City, Henan Province, China, ²Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou City, China, ³Department of Radiology, the People’s Hospital of Zhengzhou University, Zhengzhou City, Henan Province, China

Synopsis

Keywords: Tumors (Pre-Treatment), Diagnosis/Prediction

Motivation: MRF may help to distinguish the grade of glioma and ki67 increment index before operation, and help to guide the postoperative treatment.

Goal(s): The T1 and T2 values obtained by MRF are used to distinguish the grade of glioma and the ki67 proliferation coefficient.

Approach: The T1 and T2 values derived from MRF are used to predict the WHO grade of glioma and the Ki67 proliferation coefficient.

Results: The quantitative T1 and T2 values of MRF were significantly higher in low-grade gliomas and low-ki67 proliferative line groups compared to high-grade gliomas and high-ki67 proliferative line groups.

Impact: This study is helpful to predict preoperative grade of glioma and ki67 increment coefficient, and to improve the accuracy of diagnosis to some extent.

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