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Abstract #5034

Quantitative evaluation of spinal cord cine-MRI with optical flow analysis: comparison with phase contrast

Riku Iwasaki1, Tomohiko Horie1, Masateru Kawakubo2, Natsuo Konta1, Susumu Takano1, Hideki Atsumi3, and Tetsu Niwa4
1Department of Radiology, Tokai University Hospital, Kanagawa, Japan, 2Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Department of Neurosurgery, Tokai University School of Medicine, Kanagawa, Japan, 4Department of Radiology, Tokai University School of Medicine, Kanagawa, Japan

Synopsis

Keywords: Neurofluids, Neurofluids

Motivation: Spinal cord motion mechanisms remain poorly understood, especially in pathological cases.We have proposed a new technique to quantitatively evaluate spinal cord motions using optical flow analysis on spinal cord cine-MRI

Goal(s): we compared the proposed technique with the phase contrast (PC) commonly used in previous studies to investigate the similarities and differences.

Approach: Optical flow measured movement range, and phase difference analysis assessed velocity amplitude in healthy individuals and patients with Chiari I malformation and spondylotic cervical canal stenosis.

Results: In healthy subjects, movement range correlated with velocity amplitude. Chiari I malformation showed stable measures pre- and post-surgery, while stenosis cases exhibited changes.

Impact: This approach holds potential for diagnosing and evaluating spinal conditions by providing quantitative insights into spinal cord motion. It could improve clinical decision-making for Chiari I malformation , aiding in assessing treatment efficacy and patient outcomes.

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Keywords