Keywords: fMRI Analysis, CEST / APT / NOE, Differential diagnosis
Motivation: Amide proton transfer-weighted (APTw) MRI and DWI are advanced functional MR technologies that provide microstructural information about tissues. The histopathological grade of HNSCC is typically determined through invasive biopsy. Accurate and non-invasive methods are needed.
Goal(s): To investigate the potential of APTw MRI and DWI for predicting the histopathological grade of HNSCC.
Approach: Tumor grade was confirmed through pathological confirmation. APTw and ADC values were evaluated and compared across tumors with different grades.
Results: Both APTw and ADC were found to be effective in predicting the histopathological grades. The diagnostic accuracy was enhanced when both parameters were combined.
Impact: APTw and ADC provide unique insights into tumor microenvironment. Incorporating these imaging modalities into clinical practice offers a non-invasive approach for tumor grading, which could enhance preoperative assessment and potentially improve patient management.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords