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Abstract #5079

Application of Zoomit-DTI in Assessing Fetal Brain White Matter Development in Pregnancies Complicated by Maternal Diabetes

Qingqing Zhu1, Mengxiao Liu2, and Liping Deng1
1ZheJiang SirRunRun Hospital, Hangzhou, China, 2SiemensHealthineers Ltd., Shanghai, China

Synopsis

Keywords: Fetal, Fetal

Motivation: To assess the development of fetal brain white matter and sulcal maturation in pregnant women with GDM using Zoomit DTI.

Goal(s): To evaluate the differences in fetal brain white matter development between pregnant women with GDM and control pregnant women.

Approach: 16 pregnant women with GDM and 9 control pregnant women. underwent MRI examination between 31 and 37 weeks of gestation. The diffusion tensor imaging model and spherical deconvolution were applied to analyze the data.

Results: FA, MD, RD and AD values were significant differences in the GDM group and the control group.

Impact: This study reveals the microstructural differences in fetal brain white matter development in pregnant women with GDM. Zoomit - DTI may be helpful for the early diagnosis and intervention of the neurodevelopmental risks of fetuses in pregnant women with GDM.

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