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Abstract #5135

A Rapid Free-Breathing Whole-Abdomen Scan for Simultaneous T1, T2, and T2* Mapping Across Abdominal Organs

Mary Kate Manhard1,2, Anandh Kilpattu Ramaniharan1, Josh Greer2,3, Jean Tkach1,2, Andrew Trout1,2, Jonathan Dillman1,2, and Amol Pednekar1,2
1Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 2Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States, 3Philips North America, Cincinnati, OH, United States

Synopsis

Keywords: Quantitative Imaging, Acquisition Methods, Abdomen, quantitative imaging, relaxometry, MRI

Motivation: Quantitative abdominal mapping typically requires multiple scans across multiple breath-holds, with each scan providing limited anatomic coverage.

Goal(s): To evaluate the effectiveness of a rapid free-breathing whole-abdomen multiple-inversion spin-and-gradient-echo (MI-SAGE) scan for simultaneous T1, T2, and T2* mapping of various abdominal organs.

Approach: In 19 participants with and without liver disease, T1, T2, and T2* values obtained using MI-SAGE were compared to conventional mapping techniques and published values for various abdominal organs.

Results: T1, T2, and T2* estimates from MI-SAGE for multiple abdominal organs were consistent with literature, and liver and muscle values agreed with values obtained from conventional techniques.

Impact: This study demonstrates that a single one-minute, free-breathing MI-SAGE scan can achieve T1, T2, and T2* estimates across abdominal organs, comparable to published values and consistent with liver and muscle values from conventional mapping techniques from multiple breath-hold scans.

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