Abstract #5138

Motion-Robust T1/T2 Mapping of the Abdomen using Pilot-Tone Navigation

Cemre Ariyurek¹, Berkin Bilgic^2,3,4, Shohei Fujita^2,3, Yohan Jun^2,3, Sila Kurugol¹, Borjan Gagoski^1,5, and Onur Afacan¹

¹Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States, ²Department of Radiology, Harvard Medical School, Boston, MA, United States, ³Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States, ⁴Harvard/MIT Health Sciences and Technology, Cambridge, MA, United States, ⁵Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children’s Hospital, Boston, MA, United States

Synopsis

Keywords: Motion Correction, Kidney

Motivation: T1/T2 mapping in the abdomen shows promise for early tissue characterization, but standardization remains challenging due to respiratory motion.

Goal(s): To develop a motion-robust, high-resolution T1/T2 mapping technique for renal imaging to address the limitations of current quantitative renal MRI methods.

Approach: We tailored the 3D-QALAS sequence for abdominal imaging and integrated pilot-tone navigation for retrospective motion correction. The technique was tested in vivo, comparing results with and without motion correction.

Results: The proposed method successfully generated high-resolution T1/T2 maps of the kidneys without breath-holding. Motion correction improved image quality and reduced variability in T1 and T2 measurements in the kidney.

Impact: We introduce a motion-robust technique for high-resolution T1/T2 mapping of the kidneys using 3D-QALAS with pilot-tone-navigation. By overcoming respiratory motion challenges, this method could improve the accuracy and clinical applicability of quantitative renal MRI, enabling earlier detection of kidney diseases.

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