Abstract #5208

Log Subtracted Inversion Recovery

Mark Bydder¹, Daniel M Cornfeld^1,2, Paul Condron^1,2, Tracy R Melzer ^3,4, Eryn Kwon ^1,5, Maryam Tayebi ^1,5, Gil Newburn ¹, Miriam Scadeng ^2,5, Samantha J Holdsworth ^1,2, and Graeme M Bydder^1,6

¹Mātai Medical Research Institute, Gisborne, New Zealand, ²The University of Auckland, Auckland, New Zealand, ³University of Otago, Christchurch, New Zealand, ⁴New Zealand Brain Research Institute, Christchurch, New Zealand, ⁵Auckland Bioengineering Institute, Auckland, New Zealand, ⁶University of California San Diego, San Diego, CA, United States

Synopsis

Keywords: Synthetic MR, Traumatic brain injury

Motivation: This study develops a novel method for producing T₁ contrast at tissue boundaries.

Goal(s): The goal is to develop the theory and show first results from using log subtraction of in vivo images.

Approach: This is a feasibility study to produce the first images and understand the novel features.

Results: The lSIR produces high contrast images with very bright contours at tissue boundaries that help to visualize structures in areas of diffuse signal.

Impact: Use of the technique may allow clinicians to better visualize complex interfaces between tissues and to identify features in poorly characterized signal and partial volume mixtures.

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