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Abstract #5213

High-Speed Tissue Quantification Using Spatiotemporal Attention Mechanism with Undersampling Strategy Consideration

Jintao Wei1, Paween Wongkornchaovalit1, Xiaozhi Cao2,3, Zihan Zhou3,4, Qiuping Ding1, HuiHui Ye5, Jianhui Zhong6, and Hongjian He7,8
1College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China, 2Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 3Department of Radioloey, Stanford University, Stanford, CA, United States, 4Graduate school of Eduction, Stanford Universiy, Stanford, CA, United States, 5School of Communication Engineering, Hangzhou Dianzi University, Hangzhou, China, 6Department of Imaging Sciences, University of Rochester, Rochester, NY, United States, 7School of Physics, Zhejiang University, Hangzhou, China, 8State Key Laboratory of Brain-Machine Intelligence, Zhejiang University, Hangzhou, China

Synopsis

Keywords: MR Fingerprinting, AI/ML Image Reconstruction

Motivation: Current deep learning methods for accelerating MRF rely on extreme undersampling in k-space or time frames, but this is suboptimal. And the model designs struggle to fully utilize the spatiotemporal features of the data.

Goal(s): To develop a method that identifies the optimal two-dimensional undersampling combination, surpassing single-dimension undersampling in quantitative performance.

Approach: We enhanced Stolk et al.'s error model and developed a Spatiotemporal Attention with Tissue Specificity Network (STA-TS) that integrates tissue features across spatial and temporal dimensions.

Results: This approach achieves 1mm full brain coverage in 2.5 minutes, with significantly improved quantitative accuracy for T1 and T2 compared to single-dimension undersampling.

Impact: The proposed STA-TS network significantly improves MRF accuracy and efficiency, achieving full brain coverage at 1 mm resolution in just 2.5 minutes, providing a faster and more accurate imaging solution for clinical applications.

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Keywords