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Abstract #5229

IDEAL-reconstructed Seiffert Spirals for preclinical 13C metabolic MRSI at 11.7 T

Julian Schüle1, Tobias Speidel1, Fabian Bschorr1, Christoph A. Müller2, and Volker Rasche1
1Ulm University Medical Center, Ulm, Germany, 2NVision Imaging Technologies GmbH, Ulm, Germany

Synopsis

Keywords: Image Reconstruction, Image Reconstruction

Motivation: Rapid imaging methods with high temporal resolution and signal-to-noise ratio are required for hyperpolarized 13C-MRSI experiments.

Goal(s): Possible application of IDEAL-reconstructed Seiffert Spirals in a preclinical setting with respect to the requirements of hyperpolarization.

Approach: Acquisition of echo-images and IDEAL-implementation for Seiffert Spirals used for reconstruction of metabolite images using a phantom containing 13C-labeled reference solutions.

Results: Successful separation of phantom metabolites indicates possible application of Seiffert Spirals within preclinical 13C-MRSI.

Impact: The reconstructed metabolite images using Seiffert Spirals showed potential for rapid imaging with a lower number of readouts compared to other acquisition techniques in combination with IDEAL, possibly enabling single-shot trajectories to be combined with hyperpolarized probes.

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