Meeting Banner
Abstract #5240

Cryogenic RF coil versus higher magnetic field strength for 1H fast FID-MRSI in the rat brain

Thanh Phong Lê1,2, Brayan Alves1,2, Jessie Mosso1,2, Bernard Lanz1,2, and Cristina Cudalbu1,2
1CIBM Center for Biomedical Imaging, Lausanne, Switzerland, 2Animal Imaging and Technology, École polytechnique fédérale de Lausanne, Lausanne, Switzerland

Synopsis

Keywords: Spectroscopy, Brain, Proton, MRS, MRSI, FID-MRSI, Ultra-high field, Rat, Metabolic imaging

Motivation: MRSI in small rodents is challenging due to inherent low sensitivity. This could be alleviated by higher magnetic field strengths or cryogenic RF coils.

Goal(s): Compare 1H FID-MRSI in the rat brain between 9.4T with a cryogenic coil and 14.1T with a room-temperature coil.

Approach: The quality of metabolic maps obtained from both setups was compared

Results: Overall, both setups achieve metabolic quantification and mapping of similar qualities. The 9.4T setup provides better spatial coverage, higher SNR and more homogeneous B0, while the 14.1T benefits from better spectral resolution.

Impact: High quality metabolite quantification and mapping with fast 1H FID-MRSI is achieved in the rat brain benefiting from either the unmatched sensitivity of cryogenic coils at 9.4T, or enhanced spectral resolution at 14.1T.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords