Keywords: Myocardium, Cardiovascular, cardiac magnetic resonance, metabolic syndrome, resting heart rate,Restricted cubic spline
Motivation: The impact of resting heart rate (RHR) on left ventricular global longitudinal strain (LVGLS) in metabolic syndrome (MetS) patients remains unclear.
Goal(s): To investigate the association between the RHR and LVGLS in MetS patients.
Approach: Patients were grouped into 3 groups according to RHR. The association of RHR and LVGLS was assessed through multiple linear regression model, restricted cubic spline (RCS) plot and subgroup analyses.
Results: Full adjusted RCS analysis demonstrated a nonlinear association between RHR and LVGLS with the inflection point at 83. Subgroup analyses showed that this association was stable after stratification of sex, age, BMI, hypertension and type 2 diabetes.
Impact: Higher RHR is independently associated with LVGLS in patients with MetS, indicating that regular monitoring and early intervention for higher RHR may help prevent further decline in cardiac function.
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