Keywords: Myocardium, Cardiovascular
Motivation: Amino acid metabolism and obesity affect cardiac damage; however, the specific mechanism of their effect remains unclear.
Goal(s): We aimed to determine the effects of amino acid values on left ventricular cardiac function by using cardiac magnetic resonance feature tracking.
Approach: We used the b-SSFP cine sequence, CVI42 software, and mediation effect analysis.
Results: Amino acids exerted a partial mediative effect in the development of abnormal left ventricular function in an obese population, with leucine exerting the greatest mediative effect.
Impact: Our findings on the effect of amino acid metabolism and obesity on left ventricular function provide a basis for clinical management and treatment of comorbidities.
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