Keywords: Heart Failure, Cardiovascular
Motivation: To study the effects of cardiac magnetic resonance (CMR) and genetics on the prognosis of pediatric heart failure (HF) with non-ischemia.
Goal(s): To show the relationship between late gadolinium enhancement (LGE) of CMR and phenotype of genes and to explore the prognostic implications of HF.
Approach: The patients were divided into No-LGE group, Subendocardial group and No-Subendocardial group. The Phi coefficient, univariable and multivariable cox proportional hazard models and Kaplan-Meier method were assessed.
Results: MYH7 was the gene with largest proportion in this study. Non-ischemic HF can with uncommon sub-endocardial LGE and some parameters on CMR showed poor prognosis.
Impact: The study demonstrated the common genetic abnormalities in paediatric heart failure with non-ischemia and also reveal some relationship between genetics and late gadolinium enhancement. Cardiac magnetic resonance could provide valuable predictive information for pediatric heart failure with non-ischemia.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords