Meeting Banner
Abstract #5295

Improved Estimation of IVIM Parameters via Distortion and Motion Corrected DWI: Correlation with MaRIA Score in Pediatric Crohn's Disease

Cemre Ariyurek1, Lina Lu1, Valentina Valencia Ferrer1, Liam Timms1, Serge Vasylechko1, Onur Afacan1, and Sila Kurugol1
1Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Digestive, Body

Motivation: Geometric distortions and motion artifacts in diffusion-weighted MRI (DW-MRI) limit its accuracy in assessing Crohn’s disease (CD), affecting clinical evaluations.

Goal(s): This study aimed to reduce distortion and motion artifacts to improve the accuracy of intravoxel incoherent motion (IVIM) parameters obtained from DW-MRI and examine their correlation with the magnetic resonance index of activity (MaRIA)-score.

Approach: A dual-echo-EPI DW-MRI sequence with opposing encoding polarities was used for dynamic distortion correction. Motion correction was applied within and between volumes to address peristalsis and respiration.

Results: The method enhanced IVIM-MaRIA correlations and reduced IVIM parameter variability, improving the reliability of DW-MRI in evaluating CD activity.

Impact: Dual-echo EPI DW-MRI technique with dynamic distortion correction and motion compensation significantly improves the accuracy of Crohn's disease assessment, enhancing IVIM parameter estimation and correlation with disease activity scores, potentially leading to more precise diagnosis and monitoring of Crohn's disease.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords