Keywords:
Motivation: Many standard MRI brain scans fail to depict abnormalities in patients despite obvious findings in their clinical presentation. This can lead to negative health and social consequences.
Goal(s): Using ultra-high contrast (UHC) MRI we aimed to improve detection of subtle pathological changes that are invisible using standard MRI sequences.
Approach: 3D and 2D narrow and wide middle domain (mD) UHC images were acquired and compared with positionally matched conventional images.
Results: UHC MRI showed changes in disease that were inconspicuous on standard MRI images. Recovery of extensive white matter changes was seen and aligned with patient’s clinical status.
Impact: Standard MRI often fails to depict abnormalities despite changes in patient cognition, personality and/or physical state. Abnormalities can be seen in this situation with UHC MRI in otherwise normal-appearing brain, orbits and spinal cord, allowing improved diagnosis and management.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords