Using SWI as a means to better visualize the caudate nucleus in Huntingtons disease
Gollapalli L, Haacke M, Rosas D, Kwong K
Wayne State University
Research has demonstrated that longitudinal change in caudate nucleus (CN) volume could be observed over a period of time in subjects with Huntingtons disease (HD). We use susceptibility weighted imaging (SWI) to study iron changes in the CN and correlate these changes with CN volume. SWI exploits the magnetic susceptibility differences between tissues caused by varying amounts of iron.