Kemal Tuncali1, Junichi Tokuda1, Andriy Fedorov1, Iulian Iordachita2, Sam Song1, Sota Oguro1, Andras Lasso3, Fiona M. Fennessy1, Yi Tang1, Nobuhiko Hata1, Clare M. Tempany1
1Radiology, Brigham & Women's Hospital, Boston, MA, USA; 2The Johns Hopkins University, Baltimore, MD, USA; 3School of Computing, Queens University, ON, Canada
Nine patients with clinically suspected prostate cancer underwent 3T MRI-guided transperineal targeted prostate biopsy successfully in the lithotomy position without significant compications using local anesthesia and intravenous procedural sedation. Multiparametric diagnostic MRI data were registered to intraprocedural T2 weighted turbo spin echo images to facilitate targeting of index lesions. Needle location was confirmed using real-time 2D FISP. Of eight biopsy results available, two were proved cancer and six showed no malignancy. We have shown this approach to be feasible and safe. It can yield clinically useful results in patients with index lesion on diagnostic MRI.