Abstract #1422
Brain Injury and Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms after Mild Traumatic Brain Injury (BIMA): Auditory Functional Magnetic Resonance Imaging at Baseline
Priya Santhanam 1 , Peter Cartwright 2 , Thomas G Perkins 3,4 , Terrence R Oakes 1 , John Graner 1 , Gerard P Riedy 1,5 , Lindell K Weaver 6,7 , and William W Orrison 2,8
1
National Intrepid Center of Excellence
(NICoE), Bethesda, MD, United States,
2
Imgen,
LLC, Las Vegas, NV, United States,
3
Philips
Healthcare, Cleveland, OH, United States,
4
Perkins
Consultative Resources LLC, Fort Collins, CO, United
States,
5
Uniformed
Services University of the Health Sciences, Bethesda,
Maryland, United States,
6
Department of
Hyperbaric Medicine, Intermountain LDS Hospital and
Intermountain Medical Center, Salt Lake City, UT, United
States,
7
School
of Medicine, University of Utah, Salt Lake City, UT,
United States,
8
Department
of Health Physics, University of Nevada Las Vegas, Las
Vegas, NV, United States
This study seeks to examine alterations in brain
activity during an auditory task in patients with mild
traumatic brain injury (mTBI). Study participants
completed a word-listening task that was presented
unilaterally in each ear as well as bilaterally.
Comparison of three evaluation methods (clinical
radiological read, clinical computer analysis, and full
GLM analysis) was performed. Radiological score and
clinical computer analysis yielded a high degree of
concordance, and furthermore, clinical computer analysis
and GLM analysis had significant correlations. This
study demonstrates the reliability and reproducibility
of the task for evaluation of auditory deficits in an
mTBI population.
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