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Abstract #2305

Accelerated Multi-Shot Diffusion Imaging in Optic Nerve

Jr-yuan George Chiou 1 , Bruno Madore 1 , and Stephan E. Maier 1

1 Department of Radiology, Brigham and Women's Hospital, Boston, MA, United States

Quantitative MRI of the human optic nerve in vivo is generally quite challenging because of its small size, its uncontrolled motion, and the presence of local field inhomogeneity. Single-shot echo-planar imaging (EPI) is employed to obtain diffusion-weighted images within hundreds of milliseconds, but images often suffer from significant artifacts. In this study, an accelerated multi-shot diffusion imaging was employed to achieve high resolution, speed and geometric fidelity in optic nerve imaging.

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