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Abstract #3987

Imaging Ventilator-Induced Alveolar Overdistension with Hyperpolarized Xenon Diffusion MRI

Yi Xin 1 , Hooman Hamedani 1 , Maurizio Cereda 2 , Sarmad Siddiqui 1 , Mehrdad Pourfathi 1 , Harrilla Profka 1 , Stephen Kadlecek 1 , Justin Clapp 1 , Masaru Ishii 1,3 , and Rahim R. Rizi 1

1 Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2 Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States, 3 Otolaryngology, Johns Hopkins University, MD, United States

Spatial airspace dimensions can be evaluated via hyperpolarized Xenon diffusion MRI. ADC is increased in the atelectitic lung due to the alveolar overdistension, which can be mitigated by the proper recruitment strategy.

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