Abstract #1053

Aoki S, Ohtomo K, Kabasawa H, Masutani Y, Abe O

Typical diffusion anisotropy index, such as Fractional Anisotropy are accurate at single fiber but this index has its intrinsic limitation at crossing fiber. To overcome this limitation high angular resolution diffusion measurement or q-space measurement were used. However these methods requires long scan time and applying those methods to clinical is virtually impossible. In this study, diffusion properties were estimated from sparse DTI data to reduce scan time. Fiber directions were estimated by novel image processing method. Multi-directional diffusion-weighted images were analyzed with the estimated fiber directions as ga priorh information to measure diffusion properties at the crossing fiber voxel.