Accurate Quantification of Diffusion in Heterogeneous Systems Using the New Magic Asymmetric Gradient (MAG) Technique
Johns Hopkins University, Kennedy Krieger Institute
Pulsed field gradient (PFG) measurements have been used to characterize complex structures such as porous media and biological tissue. However, it is comprised of areas with strongly magnetic susceptibilities difference, leading to severe background gradients. Recently, magic asymmetric gradient (MAG) technique was proposed to suppress the cross term between applied and background gradients and can correct for contributions from varying background gradients. In this study, we showed that the MAG technique can quantify diffusion and structure accurately in heterogeneous systems. The combination of MAG and bipolar PFG techniques provides a unique contrast of quantifying varying background gradients.