Abstract #1282

Dinguizli M, Beghein N, Gallez B

In vivo EPR oximetry is a powerful method to measure oxygenation of tissues. In order to minimize diffusion and migration of paramagnetic particles in vivo, we developed a new type of thermo-reversible hydrogel (poloxamer) containing charcoal particles. This system has an interesting property: it is fluid at 5C but becomes a gel at 37C (in vivo). The purpose of this study was to examine the performance of this system in muscle and tumors