High-resolution Magic Angle Spinning (HRMAS) 1H MRS Detects Biomarkers in Pancreatic Cancer
Tzika A, Warshaw A, Lauwers G, Castillo C, Cao H
Massachusetts General Hospital and Shriners Institute, Harvard Medical School, Massachusetts General Hospital, Harvard Medical School
We report that high-resolution Magic Angle Spinning (HRMAS) 1H MRS has detected lipid accumulation in pancreatic cancer biopsies. Our findings are consistent with the hypothesis that HRMAS 1H NMR permits the identification of novel pancreatic tumor biomarkers, which can allow early diagnosis and could greatly improve prognosis.