Potential of 3D 1H MRSI localization of prostate cancer to direct TRUS guided biopsy in patients with PSA 4 10 ng/mL
Kumar V, Jagannathan N, Kumar R, Das S, Jindal L, Thulkar S, Gupta S, Dwivedi S, Hemal A, Gupta N
All India Institute of Medical Sciences
In the present study, we evaluated the usefulness of MRSI for the detection of prostate cancer foci in men with raised PSA (4-20 ng/mL) and the feasibility of directing TRUS guided biopsies at the lesions found on MRSI. MR investigations were carried out on 25 men at 1.5 Tesla (Sonata, Siemens) using endorectal coil. MRSI was used to provide z and x-coordinate of the suspicious voxel for TRUS guided biopsy. 15/25 patients showed areas of malignancy in MRSI while 5 (33%) were positive on TRUS guided biopsy. None of the patients who had a negative MRSI were positive for cancer.