Placental perfusion and permeability assessment by dual echo DCE-MRI in mice using high concentration of gadolinium.
Taillieu F, Salomon L, Vayssettes C, Ville Y, Siauve N, Clment O, Balvay D, Cuenod C
Universit Paris V Descartes, Facult Necker
This study using dual echo DCE MRI in mice with high concentration of Gd gives a non invasive access to placental microvascular parameters including the perfusion and permeability of the placental barrier. It shows promises to elucidate intrauterine growth restriction pathogenesis as well as to help in the management of compromised pregnancies.