Breast Cancer Evaluation using Diffusion Weighted MR-Imaging Prior to and Following Chemotherapy Can DWI Predict Chemotherapeutic Response?
Weatherall P, Peng Q, Ding Y, McColl R, Chia J, Tripathy D, Mason R
University of Texas Southwestern Medical Center
This pilot study involving MRI and Diffusion Weighted Imaging (DWI) of 12 subjects with breast malignancies prior to and following chemotherapy suggests that DWI may have predictive value. Patients whose tumors had very low Apparent Diffusion Coefficients (ADC)were much more likely to have a positive response to subsequent cytotoxic chemotherapy.