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Abstract #0454

On the Effects of Dephasing Due to Local Gradients in DTI Experiments: Relevance for DTI Fiber Phantoms

Frederik Bernd Laun1, Sandra Huff1, Bram Stieltjes

1Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Baden-Wrttemberg, Germany

Former versions of DTI phantoms could not be oriented arbitrarily towards B0 due to susceptibility induced local gradients. We countered this limitation by matching susceptibilities of restricting structure and fluid. This is achieved by solving sodium chloride. Thus, T2 becomes independent of orientation and diffusion measurements become reliable.