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Abstract #0614

Sodium MR Imaging at 3T Using an 8-Channel 23Na and 2-Channel 1H Rx/Tx Coil: Optimization and RF Inhomogeneity Corrections

Judy Rose James1,2, Chen Lin1, Ulrike Dydak1,2, Andriy M. Babsky1, Helmut Stark3, Brian M. Dale4, Navin Bansal1,2

1Radiology, Indiana University School of Medicine, Indianapolis, IN, USA; 2School of Health Sciences, Purdue University, West Lafayette, IN, USA; 3MRI Coils Research, Stark Contrast, Erlangen, Germany; 4Siemens Medical Solutions, Cary, NC, USA

Initial 23Na MR images of the human torso acquired at 3-Tesla using an 8-channel dual tuned 23Na/1H transmit/receive coil after RF inhomogeneity corrections are presented. 23Na images were obtained with 0.3 cm spatial resolution and ~20 SNR in ~15 min with clear delineation between different abdominal organs and their sub-regions. These images were acquired with imaging parameters optimized under SAR limits for human scans. The ability to perform 23Na MRI in clinical settings is useful to non-invasively detect and diagnose diseases in various body organs due to the physiological significance of trans-membrane sodium gradient that is critical for cell survival.