Meng Yin1, Kevin J. Glaser1, Jayant A. Talwalkar2, Armando Manduca1, Richard L. Ehman1
1Department of Radiology, Mayo Clinic, Rochester, MN, USA; 2Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN, USA
One advantage of liver MRE over biopsy or ultrasound-based transient elastography is its ability to reduce sampling error by measuring liver stiffness in multiple areas of the liver. While full 7-D wave imaging offers valid measurement of stiffness throughout the liver, the 2-D approach may also provide valid results in a significant part of the volume, with a substantially reduced imaging time. This investigation compared these two approaches, validated the key element of the protocol that makes this possible the optimized acoustic driver system can provide a wave propagation geometry that is suitable for reliable 2-D wave imaging.