Comparison of Methods Used in Calibrated FMRI

Jerod Michael Rasmussen¹, Sumiko Abe¹, Liv C. McMillan¹, Josef Pfeuffer², Jessica Turner¹, Function BIRN³

A comparison of calibration methods and their effect on the strength of correlations between: Cerebral Blood Flow (CBF), a hypercapnic task and a cognitive task. Calibration methods compared are the different permutations between active state CBF, resting state CBF, composite maps of hypercapnic breath holding and composite maps of a cognitive sensorimotor task. Each composite map has a highly temporally correlated interleaved ASL/BOLD and a traditional EPI BOLD acquisition version for comparison. Results demonstrate that using the active CBF ascertained from the interleaved ASL/BOLD acquisition method has the highest potential for calibration.