Meeting Banner
Abstract #1625

Calibration of ASL Quantification Based on Hypercapnia and Sensory Motor Activation

Sumiko Abe1, Jerod Michael Rasmussen1, Jessica Turner1, L. Ch McMillan1, Josef Pfeuffer2, F. BIRN3

1University of California, Irvine, Irvine, CA, USA; 2Siemens Medical Solutions USA Inc., USA;

To evaluate the feasibilities of quantifying cerebral perfusion with dynamic magnetic resonance artery spin labeling (ASL) sequence, we studied 4 subjects under BH and CB activities for evaluating the correlations of CBF with CMRO2 and M coefficient (i.e. CBV) with CMRO2. Based on analysis results, we confirmed that BH task increased CBF and it is not significant or weak effects to CMRO2 changes. CB task doesnt increase the GM CBF as much as BH task but CMRO2 is increased significantly due to CBF and M increasing in specified areas such as vision and motor areas.