Abstract #2149

The Effect of J-Coupling on Absolute Quantification of Liver Fat Using MRS: A Phantom Study.

Gavin Hamilton¹, Michael S. Middleton¹, Masoud Shiehmorteza¹, Claude B. Sirlin¹

¹Department of Radiology, University of California, San Diego, San Diego, CA, USA

PRESS and STEAM differ in their sensitivity to j-coupling, and as TE increases so does the effect of j-coupling. We examine, using a water-fat phantom, the effect of TE range on the observed T2-corrected fat-water peak area ratio at 3T. We found as either the minimum TE or range of TEs increased, the observed T2-corrected fat peak area also increased. This suggests using a short minimum TE and a narrow range of TEs to get greater accuracy, for both PRESS and STEAM.