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Abstract #2149

The Effect of J-Coupling on Absolute Quantification of Liver Fat Using MRS: A Phantom Study.

Gavin Hamilton1, Michael S. Middleton1, Masoud Shiehmorteza1, Claude B. Sirlin1

1Department of Radiology, University of California, San Diego, San Diego, CA, USA

PRESS and STEAM differ in their sensitivity to j-coupling, and as TE increases so does the effect of j-coupling. We examine, using a water-fat phantom, the effect of TE range on the observed T2-corrected fat-water peak area ratio at 3T. We found as either the minimum TE or range of TEs increased, the observed T2-corrected fat peak area also increased. This suggests using a short minimum TE and a narrow range of TEs to get greater accuracy, for both PRESS and STEAM.