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Abstract #2357

Cross Peak Enhancement in Constant-Time COSY (CT-COSY)

Saadallah Ramadan1, Carolyn E. Mountford1

1Radiology, Brigham and Women's Hospital, Boston, MA, USA

In vivo Localized Correlation Spectroscopy (L-COSY, 90ss 180ss t1 90ss Acq) is a developing technique that enables the researcher to un-scramble spectroscopic finding is a relatively narrow spectral bandwidth along a second dimension, and thus, facilitating analysis and improving reliability. However, when diagonal peaks are prominent, they can interfere with weak cross peaks. We propose here a CT-COSY method by which the amplitude of cross peaks can be improved and that of diagonal peaks reduced when the time delay between the leading 90o and terminal 90o increases. Theoretical reasoning is presented as well as phantom and in vivo muscle data.