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Abstract #2407

Outer-Volume Suppression Pulses to Improve In-Vivo 2D MR Spectroscopy

Roland Kreis1, Daniel Guo Quae Chong1

1Deptartment Clinical Research, University Bern, Bern, Switzerland

Outer-volume-suppression (OVS) pulses have long been used to improve localization in MRS. Recently, they were employed to improve sensitivity of PRESS for lactate that is affected by incomplete J-modulation due to the chemical shift artifact. This is also relevant in 2DJ-spectroscopy or other 2D sequences involving coherence transfer or refocusing by use of slice selective pulses. It is shown that extending a 2DJ-spectroscopy sequence with OVS pulses ameliorates spin evolution in order to 1) obtain spectra that are closer to those from ideal simulations used in 2D fitting, and 2) offer better cross-peak yield to make them more sensitive.