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Abstract #3116

A Boron/Gd/LDL Adduct for Imaging-Guided Neutron Capture Therapy

Simonetta Geninatti1, Diego Alberti, Antonio Coppino2, Ibolya Szabo2, Annamaria Deagostino3, Paolo Venturello2, Silvio Aime2

1University of Torino, Torino, Italy; 2University of Torino, Italy; 3University of torino, Italy

LDLs act as efficient carriers for the delivery of a new imaging probe containing Gd and Boron. It follows that imaging guided Boron Neutron Capture Therapy appears possible as, from the signal enhancement generated by the paramagnetic Gd(III) complexes, we access to the key information that the 10B concentration threshold has been reached.