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Abstract #3737

Improved Method for Assessing Myocardial Infarction in Rodents at 9.4T Using Delayed Enhancement-MRI

Anthony N. Price1, Kenneth K. Cheung1, Mark F. Lythgoe1

1Centre for Advanced Biomedical Imaging, UCL Institute of Child Health, University College London, London, UK

In the clinical setting delayed enhanced MRI uses inversion recovery sequences to provide the best level of contrast between MI and healthy myocardium. Relatively few studies have reported on their use in small animals, primarily due to the problems associated with rapid heart and respiratory rates, and relatively long T1 recovery times that are exhibited at high fields. In this abstract we report on the implementation of a fast inversion recovery sequence on a 9.4T experimental system for the assessment of myocardial infarction in rats during the hyper-acute phase.