Robert Staruch1, Rajiv Chopra
1University of Toronto, Toronto, ON, Canada
In order to facilitate hyperthermia-mediated drug delivery studies in small animal models, a motorized MR-guided transducer positioning system has been developed for focused ultrasound heating of rapidly scanned circular trajectories between 5 and 20mm in diameter. With this system, the temperature artifacts during simultaneous scanning and imaging were small enough to allow controlled heating, and good spatial and temporal temperature control (+/- 1 degree C) were achieved by applying multiple single-point controllers along the circular trajectory.
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