Meeting Banner
Abstract #4412

Feasibility Study of a New System for MR-Guided Scanned Focused Ultrasound Hyperthermia in Small Animals

Robert Staruch1, Rajiv Chopra

1University of Toronto, Toronto, ON, Canada

In order to facilitate hyperthermia-mediated drug delivery studies in small animal models, a motorized MR-guided transducer positioning system has been developed for focused ultrasound heating of rapidly scanned circular trajectories between 5 and 20mm in diameter. With this system, the temperature artifacts during simultaneous scanning and imaging were small enough to allow controlled heating, and good spatial and temporal temperature control (+/- 1 degree C) were achieved by applying multiple single-point controllers along the circular trajectory.