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Abstract #0154

Diffusion-Weighted Imaging of Ovarian-Related Peritoneal Carcinomatosis: Assessment of Chemotherapy Response in Relation to Anatomical Site

Stavroula Kyriazi1,2, David J. Collins1, Veronica A. Morgan2, Sharon L. Giles2, Nandita M. deSouza1,2

1CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, Surrey, United Kingdom; 2Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

Conventional biochemical and morphological criteria of chemotherapy efficacy in metastatic ovarian cancer are not sensitive in the early course of treatment and fail to reflect the frequently seen intra-patient differential response according to anatomical site of disease. The present study examines the value of Diffusion-Weighted Imaging in the early assessment of site-specific (peritoneal vs omental) chemotherapy response in ovarian-related carcinomatosis.