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Abstract #0173

Myocardial Fat Content: Single Breath-Hold 1H-MR Spectroscopy at 3 T

Belen Rial1, Stefan Neubauer1, Matthew D. Robson1, Jurgen E. Schneider1

1Cardiovascular Medicine, Oxford University, Oxford, Oxfordshire, United Kingdom

Proton MR Spectroscopy provides a window into myocardial metabolism. Cardiac and respiratory motion still degrades the sensitivity of the method and hence metabolite detection. Some techniques for reducing this problem have recently emerged, however a compromise between feasible scan duration and easy implementation of these techniques in a clinical scanner has not been reached yet. In this study we demonstrate feasible single breath-hold 1H-MR spectroscopy in the human heart at 3 T, obtaining one unsuppressed-water spectrum and three metabolite spectra, which allowed reliable quantification of fat as percentage of water content in the myocardium of healthy volunteers.