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Abstract #0986

Fast 31P Metabolic Imaging of Human Muscle

Isabell Kristin Steinseifer1, Jannie Petra Wijnen1, Bob Christian Hamans1, Arend Heerschap1, Tom Wilhelmus Scheenen1,2

1Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany

We present a 31P MRI technique to obtain images of PCr and β-ATP simultaneously by excitation of these resonances with a dual frequency selective Shinnar-LeRoux pulse at 7T. With proper choice of bandwidth of the 3D gradient echo imaging technique the chemical shift difference between the two resonances was used to completely separate images of the resonances within one large field of view. The concept of fast 31P metabolic imaging can also be applied to the brain, and even further expanded to other MR-detectable nuclei.