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Abstract #1731

Dynamic Contrast Enhanced T1-Weighted Perfusion MRI for Measuring Cerebral Perfusion Increase After Visual Stimulation

Hilde Kjeldstad Berg1, Paal Erik Goa2, Olav Haraldseth3, Henrik B W Larsson4

1HiST, Sor-Trondelag University College, Trondheim, Norway; 2Department of Diagnostic Imaging, St Olavs Hospital, Trondheim, Norway; 3Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 4Functional Imaging Unit, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark

The purpose of this study was to further develop and validate a new method for quantitative cerebral perfusion measurements, using dynamic contrast enhanced T1-weighted MR imaging. Healthy volunteers were examined in rest and during visual stimulation. Visual stimulation resulted in a significant increase in cerebral blood flow (CBF) in the occipital region, and the increase was in accordance with literature values. In other areas of the brain, CBF remained unchanged. Cerebral blood volume was also measured, but the increase observed was not found to be significant.