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Abstract #1751

Test-Retest Reproducibility of Perfusion Measurements Using PASL at 3 T

Christine Preibisch1, Annette Frschler1, Afra Wohlschlger1, Christian Sorg2, Alexander Kurz2, Claus Zimmer1, Panagiotis Alexopoulos2

1Abteilung fr Neuroradiologie, Klinikum rechts der Isar der Technischen Universitt Mnchen, Munich, Germany; 2Klinik und Poliklinik fr Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universitt Mnchen, Munich, Germany


Problem: The aim of the current study was to investigate the reproducibility of PASL imaging based on the PULSAR technique combined with thin slice periodic saturation (Q2TIPS) to control for bolus length and facilitate CBF quantification. Methods: Resting CBF maps were obtained from 16 subjects (3010a) on two different days on a 3T whole body scanner. Results: Mean CBF, within-subject standard deviation and repeatability were 34.15.3, 3.5 and 9.7 in GM and 7.42.7, 2.7and 7.5 in WM (all values in ml/100g/min). Conclusion: PULSAR based perfusion measurement shows good reproducibility lying in the range detected for other ASL methods.

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