Valerie A.
Cardenas1,2, Duygu Tosun1,2, Kristine Yaffe, 2,3,
Bruce Miller4, Norbert Schuff1,2, Michael W. Weiner1,2
1Radiology and Biomedical Imaging,
UCSF, San Francisco, CA, United States; 2San Francisco VA, San
Francisco, CA, United States; 3Neurology and Psychiatry, UCSF, San
Francisco, CA, United States; 4Memory and Aging Clinic, UCSF, San
Francisco, CA, United States
A
voxel-wise co-analysis of structural imaging and DTI is presented and
compared to analyses with a single modality only, to determine whether a
multi-modality analysis detects effects due to Alzheimer's disease with
greater sensitivity. Results show that co-analysis with FA does not detect
greater AD-related disease than structural analysis alone.