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Abstract #1943

Co-Analysis of Structural Imaging and DTI in Alzheimer's Disease

Valerie A. Cardenas1,2, Duygu Tosun1,2, Kristine Yaffe, 2,3, Bruce Miller4, Norbert Schuff1,2, Michael W. Weiner1,2

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States; 2San Francisco VA, San Francisco, CA, United States; 3Neurology and Psychiatry, UCSF, San Francisco, CA, United States; 4Memory and Aging Clinic, UCSF, San Francisco, CA, United States


A voxel-wise co-analysis of structural imaging and DTI is presented and compared to analyses with a single modality only, to determine whether a multi-modality analysis detects effects due to Alzheimer's disease with greater sensitivity. Results show that co-analysis with FA does not detect greater AD-related disease than structural analysis alone.

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