Amy Louise Kotsenas1, David W. Stanley2,
Dan W. Rettmann3, John D. Port1
1Dept. of Radiology, Mayo Clinic,
Rochester, MN, United States; 2GE Healthcare, Proctor, MN, United
States; 3GE Healthcare, Rochester, MN, United States
The
double inversion recovery (DIR) sequence supresses both cerebrospinal fluid
and white matter signal which is of benefit in detecting subtle malformations
of cortical development. Using the TI parameters from our adult DIR protocol
did not provide optimum white matter signal suppression in pediatric patients
as the T1 of the white matter varies with the degree of myelination. We were
able to determine approximate TIwm values for use in DIR sequence to optimize
the grey-white matter contrast in patients aged 1 year to 7.5 years. We were
unable to optimize white matter suppression in children under 1 year of age.
Keywords