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Abstract #2227

Quantitative Magnetization Transfer Imaging in Acute Stroke: A Follow Up Study Correlating Quantitative MRI with Respect of Severity of Stroke

Felix Jax1, Monika Gloor2, Oliver Bieri2, Meritxell Garcia1, Stefan Engelter3, Felix Fluri3, Klaus Scheffler2, E.-W. Radue1, SG Wetzel1

1Department of Neuroradiology, University of Basel Hospital, Basel, Switzerland; 2Department of Radiological Physics, University of Basel Hospital, Basel, Switzerland; 3Department of Neurology, University of Basel Hospital, Basel, Switzerland

Magnetisation transfer (MT) imaging can potentially serve as a marker for loss of tissue integrity. Moreover increased pathologic specificity is expected from quantitative MT (qMT) as compared to the assessment of the semi-quantitative MT ratio (MTR) images only. Here, we present an evaluation of qMTI data over three consecutive MRIs within the first 10 days for patients suffering from middle cerebral artery stroke with different progression of symptoms. Results seem to be superior to simple MTR measurements and possibly allow for early statement of prognosis and efficacy of therapeutic methods.