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Abstract #2228

The Assessment of Vessel Size Index and Its Application in Patients with Ischemic Stroke

Chao Xu1, Wolf Schmidt1, Peter Brunecker1, Valerij Kiselev2, Peter Gall2, Nils Bodammer3, Jochen Fiebach1

1Center for Stroke Research Berlin (CSB), Charit - Universittsmedizin Berlin, Berlin, Germany; 2Medical Physics, Department of Diagnostic Radiology, University Hospital Freiburg, Freiburg, Germany; 3Max Planck Institute for Human Development, Berlin, Germany

This study aims at implementation and evaluation of vessel size imaging (VSI) in patients with ischemic stroke. Stable values of vessel diameter have been observed in healthy volunteers in a good agreement with anatomic knowledge. VSI measurement is shown to be feasible for the clinical examination in stroke patients. Given the limitations of small number of patients, hypointensities on VSI maps in acute and chronic stage have been observed in areas of the final infarction. The recovered tissue showed normal VSI in the acute phase.