John Totenhagen1, Ivan Borbon2,
Eriko Yoshimaru1, Christine Howison3, Robert P.
Erickson2, Theodore P. Trouard1
1Biomedical Engineering, University of
Arizona, Tucson, AZ, United States; 2Pediatrics, University of
Arizona, Tucson, AZ, United States; 3Arizona Research
Laboratories, University of Arizona, Tucson, AZ, United States
Results
are presented from a longitudinal study of T2 and MRS measurements in a mouse
model of Niemann-Pick Type C (NPC) disease to examine T2 measurements and MRS
as possible indicators of disease progression and response to therapy in NPC
disease.
Keywords