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Abstract #2482

Assessing 3D Resolution of DCE-MRI for Optimization and Standardization of Breast Screening Protocols

Marco Borri1, Maria Schmidt1, Erica Scurr1, Toni Wallace1, Steven Allen1, Nandita deSouza1, Martin O. Leach1

1CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom

Spatial resolution of 3D fat-suppressed DCE pulse sequences depends on many parameters, and parity of protocols across breast screening centres is highly desirable. The objective of this work was to propose methods for quality assurance in breast screening programmes. We compared the image quality achieved with two different k-space sampling patterns, Radial and Linear, on a breast screening sequence. Resolution was evaluated with Test Objects and on Clinical Data, and, considering all three directions, was superior for Linear. The Image Analysis methodologies used were found to be robust and reproducible, and are therefore candidates to become quality assurance tools.