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Abstract #3268

Single Shot, Chemical Shift Specific Imaging Methods for Hyperpolarized Carbon-13 Studies at 14T

Subramaniam Sukumar1, Peder E.Z. Larson1, Kayvan R. Keshari1, John Kurhanewicz1, Daniel B. Vigneron1

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States

Single shot, chemical shift specific, images are demonstrated using EPI and spiral acquisition techniques at 14T. These methods address some of the problems encountered with hyperpolarized 13C MRSI at high fields related to wide spectral dispersion. Spectral-spatial pulses are designed to selectively excite only the resonances of interest. The fast, single shot acquisition methods provide high temporal resolution on the order of 50-200msec and will be applicable to time course studies involving hyperpolarized 13C.